SCIEX Addresses the Challenges of Vitamin D Measurement Standardization

Gary Horowitz, MD Medical Director, Informatics and POCT Associate Medical Director, Clinical Chemistry Department of Pathology and Laboratory Medicine Tufts Medical Center

The team has arranged for Dr. Gary Horowitz to present work done in collaboration with SCIEX. Dr. Horowitz received his bachelor’s degree in chemistry from Harvard College and his medical degree from Harvard Medical School. After completing a clinical pathology residency at Beth Israel Hospital in Boston, he went on to become the Director of Clinical Chemistry. In 1996, following the merger with New England Deaconess Hospital, he became the Director of Clinical Chemistry for the newly formed Beth Israel Deaconess Medical Center. In 2017, he joined the Department of Pathology and Laboratory Medicine at Tufts Medical Center as the Director of Informatics and Point of Care Testing, Associate Director of Clinical Chemistry, and Visiting Associate Professor of Pathology and Laboratory Medicine at Tufts University School of Medicine.

Over the past decade, 25-OH vitamin D has become one of the most common assays requested by physicians. The increase in testing volume is driven by risk-association studies linking vitamin D not only to calcium homeostasis, but also to cardiovascular disease, stroke, cancer, autoimmune disease, and even fractures. Measurement is complicated by the existence of two forms of vitamin D, as well as by the presence of epimers of both forms.

Standardization has only recently been introduced, and proficiency testing, though available, reflects the poor state of the art. In this session, we will delve into the details of vitamin D measurement, aided by results from a recent study using the first FDA-cleared via the de novo pathway 25-OH vitamin D assay for mass spectrometry. This webinar will discuss ways of acknowledging, and dealing with, limitations of the various assays.

Participants of this webinar will gain a better understanding of the need for accuracy in testing total 25-OH-vitamin D. they will also learn to recognize the importance of standardization efforts in vitamin D and how to identify the challenges of external quality control surveys face in testing accuracy.

LabRoots will host the webinar October 18, 2017, beginning at 8:00 a.m. PDT,…

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