When we target those who are at a high risk for prostate cancer based on their risk factors such as their age, family history, or body weight, then we are making it a high priority to find interventions in helping them reach a healthier body weight
August 01, 2017
With more than one-third of U.S. adults considered to be obese and with the association between obesity and prostate cancer suggesting that obesity advances the disease, there is a need to find methods that can promote weight loss. A recent randomized, double-blind, placebo controlled trial evaluated the effectiveness of decaffeinated green tea catechins (GTC) on reducing body weight or abdominal obesity but failed to produce any decrease in anthropometric variables, including changes in weight, body mass index (BMI), and abdominal obesity.
“The obesity epidemic is stronger than ever and that underscores the importance of identifying effective alternatives for men at risk of prostate cancer to help them reduce their body weight,” stated Dr. David Samadi. “Even though green tea has numerous health benefits, as far as being an answer for effective weight management, there just doesn’t appear to be sufficient evidence to show this at this time.”
Several studies have suggested that obese men with high-grade prostatic intraepithelial neoplasia (HGPIN) are more prone to experiencing advances in prostate carcinogenesis. One study found men with metabolic syndrome (abdominal obesity, hypertension, and insulin resistance) who had HGPIN at their prostate biopsy were at a higher risk for prostate cancer. HGPIN is a common histological findings on prostate biopsy and is considered to be a precursor lesion and predictor of prostate cancer.
“Americans are always looking for ways to lose weight and many turn to using nutrient supplements in a pill form as their answer,” exclaimed Dr. Samadi. “Green tea is a popular beverage and has a couple of ingredients reported to be useful in weight management – caffeine and catechins. Green tea catechins have been extensively studied on their anti-cancer mechanisms in prostate carcinogenesis but it has also been proposed that the green tea catechins may reduce body…