Diet drinks and food actually trigger weight gain and diabetes, says new study

Diet drinks or foods may actually promote weight gain and trigger diabetes because the brain misreads the number of calories present and reduces metabolism, a new study suggests.

Researchers at Yale University in the US discovered that the body stops burning energy from food if there is a ‘mismatch’ between food sweetness and calories.

In nature, sweetness signals energy and the greater the sweetness the more calories are available, so the brain has evolved to expect the two to come together. When they do not, the brain can become confused, thinking there are fewer calories to burn.

This research should be enough to convince you that artificial ingredients, whether they be in food or drink, can screw up your system

Tam Fry, National Obesity Forum

The scientists say it could help explain previous studies that have suggested that artificial sweeteners can increase blood sugar levels and possibly trigger diabetes.

“A calorie is not a calorie,” said senior author Dana Small, Professor of Psychiatry at Yale University School of Medicine.

“The assumption that more calories trigger greater metabolic and brain response is wrong. Calories are only half of the equation; sweet taste perception is the other half.

“Our bodies evolved to efficiently use the energy sources available in nature. Our modern food environment is characterized by energy sources our bodies have never seen before.

“When sweet taste and energy are not matched less energy is metabolized and weaker, or inaccurate, signals are sent to the brain.  Either one of these effects may affect metabolic health.”

The brain needs sweetness to start burning calories  Credit: Anthony Devlin PA 

For the new study, scientists scanned the brains of 15 people when they were drinking diet drinks, and compared them to regular beverages. They also monitored how much energy was burned by the body.  

They found when there was a ‘mismatch’ between sweetness and calories – as is often the case with diet drinks or foods because they are not as sugary – the calories fail to trigger the body’s metabolism. Reward circuits in the brain also did not register that calories had been consumed, which could lead to eating more.

Commenting on the paper, Dominic Dwyer, Professor of Psychology at Cardiff University, said: “What the paper does imply, correctly in my view, is that mismatches between calories and sweetness interfere with metabolism of calories in a way that could have negative impact on weight…

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