The 29-year-old – who has confirmed that she might retire from touring after 18 months on the road – told the 95,000-strong crowd to give money to the victims, after she was spotted helping out at the scene earlier this month.
Adele – who is playing four nights at Wembley this week – said: “Usually I ask everyone to get their phone out and put their lights on. But before I do that I want you to donate. Did anyone see the video before I came on? I’ve been down to Grenfell Tower.
“I’m going straight back Monday after my shows. A lot of the stories aren’t mine to tell especially on a stage like this. Today is two weeks since it happened and they are being neglected now.
“I promise any money that we raise will get to them. I am not leaving them.”
She went on: “I’m involved now. I’ll be banging on for this for days, weeks, months and years. I want everyone to donate. I know a lot of people have paid a lot of money to be here.
“If you don’t want to do it I want you to promise that you will talk about it and tell people because they are being forgotten.”
Adele added of the tragic blaze, that is thought to have killed 80 people: “I didn’t have a social conscience that long ago. You can grow one. I grew one.
“It comes with age. It’s cheaper to donate than get sh*t faced. I promise I will get the money directly in that tower.”
The star also shocked fans when she left them a handwritten note in the programme, in which she said that this could be the last time they see her on tour.
She wrote: “Touring is a peculiar thing, it doesn’t suit me particularly well. I’m a real homebody and I get so much joy in the small things. Plus I’m dramatic and have a terrible history of touring. Until now that is!
“I’ve done 119 shows and these last four will take me up to 123, it has been hard out an absolute thrill and pleasure to have done.
“I only ever did this tour for you and to hopefully have an impact on you the way that some of my favourite artist have had on me live.
“And I wanted…